The prevalence of nasal carriage methicillin-resistant Staphylococcus aureus in hospitalized patients

Moniri, R. and Moosavi, G.A. and Fadavi, N. (2009) The prevalence of nasal carriage methicillin-resistant Staphylococcus aureus in hospitalized patients. Pakistan Journal of Medical Sciences, 25 (4). pp. 656-659.

Full text not available from this repository.
Official URL: https://www.scopus.com/inward/record.uri?eid=2-s2....
DOI: UNSPECIFIED

Abstract

Objective: To determine the nasal colonization of methicillin-resistant Staphylococcus aureus in hospitalized patients. Methodology: This descriptive study was carried out on 100 hospitalized patients at Shahid Beheshti Hospital in Kashan in 2007. The nasal samples were collected by sterile swabs, and transferred to Brain Heart infusion (BHI) culture medium and immediately refered to the microbiology lab in Kashan University of Medical Sciences. Samples were inoculated on blood agar and manitol salt agar media. Identification of the isolates was done by standard biochemical tests. Oxacillin susceptibilities of S. aureus isolates were determined using Mueller-Hinton oxacillin agar screen plate. The results were analyzed statistically by chi Square and Fischer's exact tests. Results: The prevalence of nasal carriage of Staphylococcus aureus and MRSA were 38 (38 out of 100), and 52.6 (20 out of 38), respectively. The results showed that by urinary tract catheterization (P=0.005), administration of any antibiotic (p=0.008), history of diabetes mellitus (p=0.0303), and hospitalization time more than one week (p=0.0009) were the main predisposing factors for nasal colonization of MRSA. The ICU ward was the principle ward of nasal colonization by both Staphylococcus aureus (75) and MRSA (100), followed by infectious diseases ward with rates of 64.7 and 75, respectively. Conclusion: The overall colonization rate of MRSA in the hospitalized patients in this study was high. A systematic selective screening of patients with high risk of carriage should be fruitful to implement barrier precautions and reduce cross-transmission.

Item Type: Article
Additional Information: cited By 7
Uncontrolled Keywords: mannitol; oxacillin, adult; agar medium; antibiotic sensitivity; article; bacterial colonization; bacterial transmission; bacterium culture; bacterium identification; bacterium isolation; bladder catheterization; chi square test; controlled study; culture medium; descriptive research; diabetes mellitus; disease predisposition; female; Fisher exact test; high risk patient; hospital patient; human; major clinical study; male; methicillin resistant Staphylococcus aureus; nonhuman; nose; nose smear; prevalence; prospective study
Subjects: Medicine
Immunology and Microbiology
Divisions: Faculty of Medicine > Basic Sciences > Department of Microbiology & Immunology
Depositing User: editor . 2
Date Deposited: 08 Jan 2017 16:11
Last Modified: 08 Mar 2017 23:03
URI: http://eprints.kaums.ac.ir/id/eprint/957

Actions (login required)

View Item View Item