Increased risk of pre-eclampsia (PE) among women with the history of migraine

Simbar, M. and Karimian, Z. and Afrakhteh, M. and Akbarzadeh, A. and Kouchaki, E. (2010) Increased risk of pre-eclampsia (PE) among women with the history of migraine. Clinical and Experimental Hypertension, 32 (3). pp. 159-165. ISSN 1064-1963

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The Objective of this study was to assess possible association of history of migraine with pre-eclampsia (PE). This was a retrospective study to compare history of migraine in 90 women affected by PE with 90 women without PE as the control group. They recruited by a nonrandomized consecutive sampling method. Data were collected by a questionnaire including demographic, medical, obstetrics, and migraine assessment sections. Data were analyzed using SPSS. Results showed an increased risk of PE in women with history of migraine (odds ratio: 2.87; p < 0.05). Result demonstrated that migraine history in the case group is 144 and in control group is 56. Gestational age (GA) at delivery and weight of neonate (WN) were significantly lower compared to control (GA: 37.3 ± 2.6 vs. 38.7± 1.3 weeks T test; P < 0.01) (WN: 2930 ± 690 vs. 3330 ± 420; T test; P < 0.0). Cesarean section was more frequent in the PE group compared to the control group 37 (42) vs. 14 (15.6); chi square; p < 0.01. The association of migraine with PE is the result of some similar mechanism leading to endothelial dysfunction. Frequent reports of an association between migraine and PE in different populations suggest a history of migraine as a risk factor for PEgestational hypertension (GH). Copyright © Informa UK Ltd.

Item Type: Article
Additional Information: cited By 7
Uncontrolled Keywords: adult; anamnesis; article; birth weight; case control study; cesarean section; controlled study; disease association; disease classification; endothelial dysfunction; female; gestational age; high risk population; human; Iran; major clinical study; maternal hypertension; migraine; pain assessment; patient assessment; preeclampsia; questionnaire; retrospective study; risk factor, Adult; Case-Control Studies; Female; Gestational Age; Humans; Infant, Newborn; Iran; Migraine Disorders; Pre-Eclampsia; Pregnancy; Retrospective Studies; Risk Factors; Young Adult
Subjects: Medicine
Divisions: Faculty of Medicine > Clinical Sciences > Department of Neurosurgery
Depositing User: editor . 2
Date Deposited: 28 Jan 2017 17:12
Last Modified: 11 Mar 2017 15:58

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