Maternal haemodynamic effects of oxytocin bolus or infusion in the third stage of labour

Foroozanfard, F. and Sadat, Z. and Moosavi, G.A. and Hatami, L. (2011) Maternal haemodynamic effects of oxytocin bolus or infusion in the third stage of labour. Pakistan Journal of Medical Sciences, 27 (3). pp. 656-659.

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Abstract

Objectives: The safety of bolus oxytocin has been questioned due to reports of maternal hemodynamic consequences. This study compared maternal haemodynamic effects of oxytocin bolus or infusion in the third stage of vaginal delivery. Methodology: This was a randomized double-blind clinical trial in 170 women who received (10IU) intravenous oxytocin bolus or infusion in third stage of labour. Mean arterial pressure (MAP) and heart rate (HR) were measured before delivery and 1, 5, 10, 20 minutes after administration of oxytocin. These serial measurements and postpartum outcome were compared in two groups. Results were analyzed using analysis of variance for repeated measures, t-test, Man U Whitney, Fisher exact test, and chi-square test. Results: Findings showed MAP and HR did not vary between two groups (p= 0.38 and p= 0.65 respectively. Length of the third stage of labour, retained placenta and reduction in haemoglobin concentration for the bolus group was less than infusion group (p=0.000, p=0.042 and P=0.036 respectively). Other postpartum outcome was similar in two groups. Conclusion: Bolus oxytocin is not associated with adverse maternal hemodynamics and appeared to be as effective and can safely be administered in the third stage of labour.

Item Type: Article
Additional Information: cited By 1
Uncontrolled Keywords: hemoglobin; oxytocin, adult; article; birth weight; bolus injection; controlled study; double blind procedure; female; gestational age; heart rate; hemodynamics; hemoglobin blood level; human; labor stage 2; labor stage 3; lithotomy position; mean arterial pressure; outcome assessment; parity; postpartum hemorrhage; puerperium; randomized controlled trial; retained placenta; vaginal delivery
Subjects: Nursing
Divisions: Faculty of Nursing & Midwifery > Department of Midwifery
Depositing User: editor . 2
Date Deposited: 27 Feb 2017 05:41
Last Modified: 04 Mar 2017 05:51
URI: http://eprints.kaums.ac.ir/id/eprint/867

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