Effects of zinc supplementation on glycemic control and complications of gestational diabetes

Mahdian, M. and Behrashi, M. and Aliasgharzadeh, A. (2011) Effects of zinc supplementation on glycemic control and complications of gestational diabetes. Pakistan Journal of Medical Sciences, 27 (5). pp. 1203-1206.

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Objectives: To investigate the effects of zinc supplementation on pregnancy outcome in patients with gestational diabetes mellitus. Methodology: During the randomized double blind clinical trial 60 women with gestational diabetes mellitus from 32 nd of gestational age were assigned to two equal groups to receive 25mg zinc sulfate orally per day as case or placebo as control. Then, groups were compared regarding insulin dosage needs, macrosomia and preeclampsia. Results: Insulin requirements and dosage changes during the investigation were lower in the case group than in the control (P<0.001). Women in the zinc supplemental group had a lower percentage of large infants compared to control (P<0.01). There were no significant differences between two groups regarding the rates of preeclampsia and cesarean delivery. Conclusions: This study showed that zinc supplementation in gestational diabetes could reduce insulin needs and improve glycemic control of these patients and it may also reduce macrosomia.

Item Type: Article
Additional Information: cited By 0
Uncontrolled Keywords: glucose; insulin; placebo; zinc sulfate, adult; article; cesarean section; controlled study; diet supplementation; double blind procedure; female; gestational age; glycemic control; human; macrosomia; major clinical study; preeclampsia; pregnancy diabetes mellitus; pregnancy outcome; randomized controlled trial; treatment outcome
Subjects: Medicine
Biochemistry, Genetics and Molecular Biology
Divisions: Faculty of Para medicine > Department of Management Anesthesia
Depositing User: editor . 2
Date Deposited: 27 Feb 2017 09:37
Last Modified: 11 Mar 2017 13:50
URI: http://eprints.kaums.ac.ir/id/eprint/812

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