Evaluation of health related quality of life in irritable bowel syndrome patients

Jamali, R. and Jamali, A. and Poorrahnama, M. and Omidi, A. and Jamali, B. and Moslemi, N. and Ansari, R. and Dolatshahi, S. and Ebrahimi Daryani, N. (2012) Evaluation of health related quality of life in irritable bowel syndrome patients. Health and Quality of Life Outcomes, 10.

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Background: Quality of life (QOL) is an important measure in the management of Irritable Bowel Syndrome (IBS). Controversy exists in the findings of studies evaluating QOL in IBS subtypes, and little is known about this issue in Iranian patients. Determination of the factors affecting QOL in IBS patients may influence treatment outcomes. The aims of this study are to: 1) compare QOL between subtypes in a sample of Iranian IBS patients, 2) determine the factors associated with QOL in IBS.Methods: This cross sectional study included two hundred and fifty IBS patients with the mean age (± standard deviation) of 31.62 (± 11.93) years that were referred to outpatient gastroenterology clinic. IBS patients were diagnosed based on Rome-3 criteria by a gastroenterologist, and then they were categorized into three subtypes according to the predominant type of bowel habit. The "QOL specific for IBS", "Stait-trait anxiety inventory", and "Beck depression inventory-2" questioners were used to evaluate QOL, anxiety, and depression symptoms, respectively.Results: The mean QOL scores in IBS mixed subtype (71.7 ± 25.57), constipation predominant subtype (80.28 ± 25.57), and diarrhea predominant subtype (76.43 ± 19.13) were not different. (P value: 0.05) In multivariate linear regression analysis, anxiety symptom scores were inversely correlated with QOL scores. Standardized beta: -0.43, (95% confidence interval: -0.70, -0.39), P value: < 0.01. Conclusion: It seems reasonable to manage anxiety symptoms properly in IBS patients since this might increase their QOL. © 2012 Jamali et al; licensee BioMed Central Ltd.

Item Type: Article
Additional Information: cited By 18
Uncontrolled Keywords: adolescent; adult; anxiety; article; Beck Depression Inventory; cross-sectional study; depression; disease severity; human; irritable colon; major clinical study; quality of life; State Trait Anxiety Inventory; age distribution; anxiety; comparative study; constipation; depression; diarrhea; evaluation; female; hospitalization; Iran; irritable colon; male; middle aged; multivariate analysis; psychological aspect; psychometry; questionnaire; risk assessment; sex ratio; Sickness Impact Profile; statistical model, Adult; Age Distribution; Anxiety; Constipation; Cross-Sectional Studies; Depressive Disorder; Diarrhea; Female; Humans; Iran; Irritable Bowel Syndrome; Linear Models; Male; Middle Aged; Multivariate Analysis; Psychometrics; Quality of Life; Questionnaires; Risk Assessment; Severity of Illness Index; Sex Distribution; Sickness Impact Profile; Young Adult
Subjects: Medicine
Divisions: Faculty of Medicine > Clinical Sciences > Department of Internal Medicine
Depositing User: editor . 2
Date Deposited: 28 Feb 2017 15:57
Last Modified: 28 Feb 2017 15:57
URI: http://eprints.kaums.ac.ir/id/eprint/797

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