The value of touch preparation for rapid diagnosis of brain tumors as an intraoperative consultation

Khamechian, T. and Alizargar, J. and Mazoochi, T. (2012) The value of touch preparation for rapid diagnosis of brain tumors as an intraoperative consultation. Iranian Journal of Medical Sciences, 37 (2). pp. 105-111.

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Background: The touch preparation technique is an accurate and rapid method, and when used as intraoperative consultation examination technique it preserves a good amount of tissue for paraffin embedded sections. This study aimed at examining the accuracy of the touch preparation technique by comparing its diagnosis with that of final pathological diagnosis made by microscopic examinations. Methods: The diagnoses of 139 central nervous system lesions by touch preparation technique and paraffin-embedded sections were compared. Results: Touch preparation technique diagnosed correctly 118 (84) of the lesions. However, the technique failed to correctly diagnose 12 of the cases. The highest rate of accurate diagnosis (100) was observed in five types out of 11 types of tumor examined. However, the technique was not able to diagnose hydatid cysts correctly. Conclusion: The findings indicate that touch preparation technique may be useful in diagnosing tumor type during surgical operations. Touch preparation technique is very accurate for intraoperative diagnosis. However, adequate clinical history, neuroimaging details, and the intraoperative impressions of the neurosurgeons, if provided, help the pathologists to improve the diagnostic accuracy of the technique.

Item Type: Article
Additional Information: cited By 0
Uncontrolled Keywords: acute megakaryocytic leukemia; adult; article; astrocytoma; brain tumor; cancer grading; choroid plexus papilloma; clinical evaluation; controlled study; craniopharyngioma; diagnostic accuracy; diagnostic error; diagnostic procedure; diagnostic value; echinococcosis; female; giant cell tumor; glioblastoma; hemangioblastoma; human; human tissue; hypophysis adenoma; intermethod comparison; intraoperative period; major clinical study; male; medulloblastoma; meningioma; metastasis; microscopy; neurilemoma; oligodendroglioma; prediction; reliability; sensitivity and specificity; teratoma; touch preparation technique; tumor necrosis
Subjects: Pathology
Divisions: Faculty of Medicine > Basic Sciences > Department of Pathology& Histology
Depositing User: editor . 2
Date Deposited: 28 Feb 2017 16:02
Last Modified: 28 Feb 2017 16:02

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