Effect of daily consumption of probiotic yoghurt on lipid profiles in pregnant women: A randomized controlled clinical trial

Asemi, Z. and Samimi, M. and Tabassi, Z. and Talebian, P. and Azarbad, Z. and Hydarzadeh, Z. and Esmaillzadeh, A. (2012) Effect of daily consumption of probiotic yoghurt on lipid profiles in pregnant women: A randomized controlled clinical trial. Journal of Maternal-Fetal and Neonatal Medicine, 25 (9). pp. 1552-1556.

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Abstract

Background: Due to enhanced fat storage primarily during the mid-pregnancy period, pregnancy is associated with elevated levels of lipid profiles. To our knowledge, no reports are available indicating the effects of probiotic yoghurt consumption on serum lipid profiles in pregnant women. Objective: This study was designed to determine the effects of daily consumption of probiotic yoghurt on lipid profiles of Iranian pregnant women. Methods: This randomized single-blinded controlled clinical trial was performed among 70 pregnant women, primigravida, aged 1830 years old who were carrying singleton pregnancy at their third trimester. Subjects were randomly assigned to consume 200g/d of conventional (n33) or the probiotic group (n37) for 9 weeks. The probiotic yoghurt was a commercially available product prepared with the starter cultures of Streptococcus thermophilus and Lactobacillus bulgaricus, enriched with probiotic culture of two strains of lactobacilli (Lactobacillus acidophilus LA5) and bifidobacteria (Bifidobacterium animalis BB12) with a total of min 1�107 colony-forming units. The conventional yoghurt contained the starter cultures of S. thermophilus and L. bulgaricus. Fasting blood samples were taken at baseline and after 9-weeks intervention to measure serum lipid profiles. Results: Although consumption of probiotic yogurt for 9 weeks had been resulted in a significant reduction in serum total-(-53.7mg/dL, p0.001), LDL-(-35.2mg/dL, p0.006) and HDL-cholesterol levels (-9.8mg/dL, p0.002) as well as serum triglyceride concentrations (-42.8mg/dL, p0.029), no significant differences were found comparing probiotic and conventional yogurts in terms of their effect on serum lipid profiles. Within-Group differences in conventional yogurt group revealed a significant reduction in HDL-cholesterol levels (-8.4mg/dL, p0.005) and borderline significant reduction in serum total cholesterol concentrations (-21.6mg/dL, p0.08). Conclusion: In conclusion, consumption of probiotic yogurt among pregnant women could not affect serum lipid profiles as compared to the conventional yogurt. © 2012 Informa UK, Ltd.

Item Type: Article
Additional Information: cited By 16
Uncontrolled Keywords: high density lipoprotein cholesterol; lipid; low density lipoprotein cholesterol; triacylglycerol; yoghurt, adult; article; Bifidobacterium animalis; cholesterol blood level; controlled study; female; food intake; human; Iran; Lactobacillus; Lactobacillus acidophilus; lactobacillus bulgaricus; lipid blood level; major clinical study; pregnancy; priority journal; randomized controlled trial; single blind procedure; starter culture; Streptococcus thermophilus; third trimester pregnancy; triacylglycerol blood level, Adolescent; Adult; Bifidobacterium; Feeding Behavior; Female; Humans; Lactobacillus acidophilus; Lipid Metabolism; Lipids; Pregnancy; Pregnancy Trimester, Third; Pregnant Women; Probiotics; Single-Blind Method; Yogurt; Young Adult
Subjects: Nutrition
Divisions: Faculty of Medicine > Basic Sciences > Department of Nutrition
Depositing User: editor . 2
Date Deposited: 28 Feb 2017 16:21
Last Modified: 08 Mar 2017 21:41
URI: http://eprints.kaums.ac.ir/id/eprint/757

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