Effect of sesame on sperm quality of infertile men

Khani, B. and Bidgoli, S.R. and Moattar, F. and Hassani, H. (2013) Effect of sesame on sperm quality of infertile men. Journal of Research in Medical Sciences, 18 (3). pp. 184-187.

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Background: High level of semen reactive oxygen species is considered as an important factor in male infertility. Sesame has antioxidant properties, which could be effective on improvement of semen parameters. This study was designed to determine the effects of sesame on sperm quality. Materials and Methods: Twenty-five infertile men entered this clinical trial. They were treated with a 3-months course of taking 0.5mg/kg sesame. The pre intervention sperm analysis (sperm count, motile sperm percentage and normal morphology sperm percentage) was compared with post treatment sperm analysis. Based on the post intervention seamen analysis, patients were advised to undergo either IVF or ICSI to assess their fertility status. Results: There was significant improvement in the sperm count (10.56±5.25vs. 22.71±30.14 million per ml) and motility (15.32±13.58vs. 23.32±20.61 percent) after treatment with sesame (Pvalue: 0.04 and <0.0001 respectively), but there was no significant improvement in sperm morphology after the treatment (10.72±6.66vs. 13.20±11.14 percent, Pvalue: 0.10). Three patients (12) underwent IUI, which resulted in 1 successful pregnancy. Two patients (8) underwent ICSI, which was not successful; however2(8) patients had spontaneous pregnancy. Fortunately, all pregnancies led to live birth. Except 1case of diarrhea, no other major side effect was reported. Conclusion: Sesame improved sperm count and motility, and can be prescribed as an effective and safe method for male factor infertility.

Item Type: Article
Additional Information: cited By 3
Uncontrolled Keywords: adult; article; clinical article; clinical trial; diarrhea; fertilization in vitro; human; intracytoplasmic sperm injection; intrauterine insemination; live birth; male; male genital tract parameters; male infertility; pregnancy; semen analysis; sesame; sperm quality; spermatozoon count; spermatozoon motility
Subjects: Anatomy Morphology
Divisions: Faculty of Medicine > Basic Sciences > Department of Anatomy
Depositing User: editor . 2
Date Deposited: 03 Mar 2017 13:39
Last Modified: 03 Mar 2017 13:39
URI: http://eprints.kaums.ac.ir/id/eprint/672

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