Seroprevalence of anti-hepatitis a antibody among 1 - 15 year old children in Kashan-Iran

Taghavi-Ardakani, A. and Soltani, B. and Sehat, M. and Namjoo, S. and Haji Rezaei, M. (2013) Seroprevalence of anti-hepatitis a antibody among 1 - 15 year old children in Kashan-Iran. Hepatitis Monthly, 13 (5).

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Background: Worldwide, hepatitis A is a common infection during childhood especially in developing countries. It can cause severe complications in adults and patients with underlying diseases. Objectives: This study was performed to determine the seroprevalence of hepatitis A in 1 - 15 year-old children of Kashan. Patients and Methods: This cross-sectional study was performed on 666 one to fifteen year-old children from health-care centers in Kashan city during 2012. Total antibodies against hepatitis A were measured in sera by enzyme-linked immunosorbent assay (ELISA). Results: Totally, 3.9 of children were seropositive. Mean number of family members was 3.92 ± 0.89. There was no difference in seroprevalence of hepatitis A relative to sex, family size, mean age and age groups. Conclusions: In this city, a great proportion of children are susceptible to hepatitis A and it's complications at an older age. This decrease in seropositivity may be caused by elevated hygien level. According to our results hepatitis A vaccination is recommended at early childhood such as that of other regions where low prevalence of hepatitis A infection is found. © 2013, Kowsar Corp.

Item Type: Article
Additional Information: cited By 8
Uncontrolled Keywords: hepatitis A antibody; hepatitis A vaccine; immunoglobulin G; immunoglobulin M, adolescent; article; child; cross-sectional study; enzyme linked immunosorbent assay; female; hepatitis A; human; infant; major clinical study; male; preschool child; questionnaire; risk factor; school child; seroprevalence
Subjects: Medicine
Divisions: Faculty of Medicine > Clinical Sciences > Department of Pediatrics
Depositing User: editor . 2
Date Deposited: 03 Mar 2017 14:23
Last Modified: 03 Mar 2017 14:23

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