Antimicrobial and antioxidant activities of Pycnocycla spinosa extracts

Mahboubi, M. and Taghizadeh, M. and Kazempour, N. (2014) Antimicrobial and antioxidant activities of Pycnocycla spinosa extracts. Jundishapur Journal of Natural Pharmaceutical Products, 9 (3).

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Background: Pycnocycla spinosa (P. spinosa) a member of the Umbelliferae family is traditionally used for treatment of different ailments. Objectives: This study aimed to evaluate the total phenolic and flavonoid content of P. spinosa extracts (methanol, ethanol and aqueous) and their antioxidant and antimicrobial effects. Materials and Methods: The antimicrobial activity of different extracts of P. spinosa was evaluated using micro broth dilution. Total phenolic and flavonoid contents were measured. Their antioxidant effect was evaluated using DPPH assay and �-carotene linoleic acid test. Results: P. spinosa ethanol extract with higher-level phenolic and flavonoid contents showed the highest antioxidant and antimicrobial effects, in comparison with the other extracts. Bacillus sp. and Streptococcus sp. showed higher sensitivity to P. spinosa ethanol extract. Conclusions: P. spinosa ethanol extract can be used as a mouthwash for treatment of the oral infections. More clinical and toxicological studies are required for providing its efficacy. © 2014, School of Pharmacy, Ahvaz Jundishapur University of Medical Sciences.

Item Type: Article
Additional Information: cited By 1
Uncontrolled Keywords: alcohol; beta carotene; flavonoid; linoleic acid; methanol; phenol derivative; plant extract; Pycnocycla spinosa extract; unclassified drug, antibiotic sensitivity; antimicrobial activity; antioxidant activity; Apiaceae; aqueous solution; article; Bacillus cereus; Bacillus subtilis; broth dilution; DPPH radical scavenging assay; micro broth dilution; minimum inhibitory concentration; minimum lethal concentration; nonhuman; pharmacological parameters; Pycnocycla spinosa; Staphylococcus aureus; Staphylococcus epidermidis; Streptococcus agalactiae; Streptococcus mutans; Streptococcus salivarius; Streptococcus sanguinis; Streptococcus sobrinus
Subjects: Immunology and Microbiology
Divisions: Faculty of Medicine > Basic Sciences > Department of Nutrition
Depositing User: editor . 2
Date Deposited: 05 Mar 2017 08:42
Last Modified: 05 Mar 2017 08:42

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