Resveratrol is a promising agent for colorectal cancer prevention and treatment: Focus on molecular mechanisms

Honari, M. and Shafabakhsh, R. and Reiter, R.J. and Mirzaei, H. and Asemi, Z. (2019) Resveratrol is a promising agent for colorectal cancer prevention and treatment: Focus on molecular mechanisms. Cancer Cell International, 19 (1).

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Abstract

Colorectal cancer (CRC) is the third most common cancer and one of the main causes of cancer death entire the world. Environmental, dietary, and lifestyle factors including red meat consumption, cigarette smoking, alcohol intake and family history are the most important risk factors of CRC. Multiple pathways including inflammation, oxidative stress, and apoptosis are involved in its incidence and progression. Resveratrol, a polyphenolic compound, has different pharmacologic functions including anti-inflammation, cancer prevention, lipid-lowering effect, and hypoglycemic effect. Many studies have proved that resveratrol might also represent a chemo preventive effect on CRC. Thus, the aim of the current review is to depict the role of resveratrol in treatment of CRC in a molecular manner. © 2019 The Author(s).

Item Type: Article
Additional Information: cited By 0
Uncontrolled Keywords: resveratrol, antiinflammatory activity; antineoplastic activity; cancer prevention; cell survival; clinical effectiveness; clinical trial (topic); colorectal cancer; drug effect; drug efficacy; drug mechanism; drug response; human; nonhuman; oxidative stress; Review; treatment outcome
Subjects: Biochemistry, Genetics and Molecular Biology
Depositing User: ART . editor
Date Deposited: 31 Dec 2019 11:04
Last Modified: 31 Dec 2019 11:04
URI: http://eprints.kaums.ac.ir/id/eprint/4505

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