The effects of caffeine intake on weight loss: a systematic review and dos-response meta-analysis of randomized controlled trials

Tabrizi, R. and Saneei, P. and Lankarani, K.B. and Akbari, M. and Kolahdooz, F. and Esmaillzadeh, A. and Nadi-Ravandi, S. and Mazoochi, M. and Asemi, Z. (2019) The effects of caffeine intake on weight loss: a systematic review and dos-response meta-analysis of randomized controlled trials. Critical Reviews in Food Science and Nutrition, 59 (16). pp. 2688-2696.

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Abstract

This systematic review and meta-analysis of randomized controlled trials (RCTs) was performed to summarize the effect of caffeine intake on weight loss. We searched the following databases until November 2017: MEDLINE, EMBASE, Web of Science, and Cochrane Central Register of Controlled Trials. The relevant data were extracted and assessed for quality of the studies according to the Cochrane risk of bias tool. We estimated an intake-status regression coefficient (Beta) for each primary study and estimated the overall pooled Beta and SE using random effects meta-analysis on a double-log scale. Heterogeneity between studies was assessed by the Cochran Q statistic and I-squared tests (I2). Thirteen RCTs with 606 participants were included in the meta-analyses. The overall pooled Beta for the effect of caffeine intake was 0.29 (95CI: 0.19, 0.40; Q = 124.5, I2 = 91.2) for weigh, 0.23 (95CI: 0.09, 0.36; Q = 71.0, I2 = 93.0) for BMI, and 0.36 (95 CI: 0.24, 0.48; Q = 167.36, I2 = 94.0) for fat mass. For every doubling in caffeine intake, the mean reduction in weight, BMI, and fat mass increased 2 Beta-fold (20.29 = 1.22, 20.23 = 1.17, and 20.36 = 1.28), which corresponding to 22, 17, and 28 percent, respectively. Overall, the current meta-analysis demonstrated that caffeine intake might promote weight, BMI and body fat reduction. © 2018, © 2018 Taylor & Francis Group, LLC.

Item Type: Article
Additional Information: cited By 1
Uncontrolled Keywords: Caffeine; Health; Random processes, Body fat reductions; Controlled trial; Mean reductions; Meta analysis; Randomized controlled trial; Regression coefficient; Systematic Review; Weight loss, Risk assessment
Subjects: Nutrition
Divisions: Faculty of Medicine > Basic Sciences > Department of Nutrition
Depositing User: ART . editor
Date Deposited: 01 Jan 2020 11:30
Last Modified: 01 Jan 2020 11:30
URI: http://eprints.kaums.ac.ir/id/eprint/4448

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