Prevalence and probabilistic health risk assessment of aflatoxins B1, B2, G1, and G2 in Iranian edible oils

Nabizadeh, S. and Shariatifar, N. and Shokoohi, E. and Shoeibi, S. and Gavahian, M. and Fakhri, Y. and Azari, A. and Mousavi Khaneghah, A. (2018) Prevalence and probabilistic health risk assessment of aflatoxins B1, B2, G1, and G2 in Iranian edible oils. Environmental Science and Pollution Research, 25 (35). pp. 35562-35570.

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Abstract

The prevalence of aflatoxins (AFs) B1, B2, G1, and G2 in Iranian edible oils were assessed by immunoaffinity column cleanup and HPLC equipped with a fluorescence detector (HPLC-FLD). Ninety-seven samples including sunflower, canola, refined olive, unrefined olive, frying, and blend oils were collected from eight provinces (n = 15 samples of refined olive oil, n = 15 samples of unrefined olive oil, n = 15 samples of sunflower oil, n = 15 samples of canola oil, n = 17 samples of frying oil, and n = 20 samples of blend oil). Also, cancer risk of aflatoxins in the adults and children due to ingestion of edible oils was estimated via margin of exposure (MOE) estimation in the Monte Carlo simulation (MCS) model. Considering the limit of detection (LOD) of the current study, two unrefined olive oil samples from Zanjan Province were contaminated with AFB2 in the concentrations of 0.2 and 0.4 ng/g while other samples were free from AFB1, AFB2, AFG1, and AFG2. This study revealed that about 98 of the collected samples were free from AFs and the concentrations of AFs in the polluted samples were within the standard range suggested by European Commission regulation (20 μg/kg). However, health risk assessment indicated that both adult and children in the Zanjan Province are at considerable liver cancer risk (percentile 95 of MOE < 10,000 value). Therefore, national plan to address this issue and strict inspection of edible oil products by the regulatory bodies are suggested. © 2018, Springer-Verlag GmbH Germany, part of Springer Nature.

Item Type: Article
Additional Information: cited By 0
Uncontrolled Keywords: cancer; child health; cleanup; detection method; disease prevalence; European Commission; health risk; immune system; liquid chromatography; probability; risk assessment; toxin; vegetable oil, Iran; Zanjan, Brassica napus var. napus; Helianthus, aflatoxin; aflatoxin B1; aflatoxin B2; aflatoxin G1; aflatoxin G2; vegetable oil, adult; analysis; chemistry; child; edible plant; food contamination; high performance liquid chromatography; human; Iran; limit of detection; prevalence; probability; reproducibility; risk assessment; statistics and numerical data, Adult; Aflatoxin B1; Aflatoxins; Child; Chromatography, High Pressure Liquid; Food Contamination; Humans; Iran; Limit of Detection; Plant Oils; Plants, Edible; Prevalence; Probability; Reproducibility of Results; Risk Assessment
Subjects: Health Professions
Divisions: Faculty of Health > Department of Environmental health
Depositing User: ART . editor
Date Deposited: 22 Apr 2019 14:48
Last Modified: 22 Apr 2019 14:48
URI: http://eprints.kaums.ac.ir/id/eprint/3804

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