An update on lead poisoning

Rafati-Rahimzadeh, M. and Rafati-Rahimzadeh, M.R. and Kazemi, S. and Moghaddamnia, A.A. (2015) An update on lead poisoning. Journal of Babol University of Medical Sciences, 17 (3). pp. 35-50.

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Background and objective: Lead poisoning have been reported from many parts of the world. They are one of global clinical problem that effect all body organs and many deaths every year. This review was done to survey toxicological aspects of lead compounds Methods: The data bank used in this study is web of science, scopus, pubmed, pubmed central, SID. The keywords are Alzheimer�s Disease, medical plants, acetylcholine, antioxidant. Findings: Metallic lead is used industrial, organic lead eg., tetraethyl and tetramethyl lead in gasoline additives to prevent engine knock, and inorganic lead salts combined with other elements. Majority of absorptive lead through the respiratory and gastrointestinal systems. Lead compounds can lead to clinical manifestation in neurologic system, hematopoietic, kidneys, cardiovascular, reproduction, bones. There are tests available to diagnose poisoning by measuring lead in blood, urine, hair and fingernails. Patients of lead toxicity need to decontamination (GI tract irrigation), supportive cares, use traditional and new chelating agents to combination therapy, also antioxidants, vitamins, and nanoparticle. Conclusion: Based on the survey, it is recommended to detect contaminated areas and consider an educational plan for the exposed people to prevention of lead poisoning. © 2015, Babol University of Medical Sciences. All right reserved.

Item Type: Article
Additional Information: cited By 0
Uncontrolled Keywords: antioxidant; chelating agent; lead; nanoparticle; tetraethyllead; tetramethyllead; vitamin, Article; finger nail; gastrointestinal irritation; hair analysis; health survey; intestine lavage; lead blood level; lead poisoning; skin decontamination; urinalysis
Subjects: Biochemistry, Genetics and Molecular Biology
Divisions: Faculty of Para medicine > Department of Management Radiology and Medical Physics
Depositing User: editor . 2
Date Deposited: 07 Mar 2017 16:25
Last Modified: 07 Mar 2017 16:25

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