The effect of evening primrose oil on fatigue and quality of life in patients with multiple sclerosis

Majdinasab, N. and Namjoyan, F. and Taghizadeh, M. and Saki, H. (2018) The effect of evening primrose oil on fatigue and quality of life in patients with multiple sclerosis. Neuropsychiatric Disease and Treatment, 14. pp. 1505-1512.

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Abstract

Abstract Background Multiple sclerosis (MS) is a chronic progressive and inflammatory disease of the central nervous system that is characterized by demyelination in the central nervous system. In regard to the prevalence of diseases and enormous costs imposed on society and the health system, finding a way to stop the progression of the disease using drugs with fewer side effects seems a serious sanitation issue to the health of the international community. This study aimed to evaluate the effect of evening primrose oil (EPO) on fatigue and quality of life in patients with MS. Materials and methods In this double-blind randomized clinical trial, 52 patients with MS were chosen and categorized into 2 groups which received 2 doses of EPO and placebo. In addition, the quality of life and fatigue scale in these patients were investigated before the treatment and again 3 months after therapy. The findings were then compared between the 2 groups. Result EPO consumption significantly increased cognitive function, vitality, and overall life satisfaction and also reduced pain and fatigue compared to placebo (P<0.05). Conclusion Our findings indicated that EPO consumption had no impact on the quality of life in general; however, it had a significant effect on several important aspects of life quality such as the increase of cognitive function, vitality, and overall life satisfaction. It also reduced the pain and fatigue in comparison to the placebo consumption. Herbal medicines are brittle and have fewer side effects than chemical drugs. With use of this plant, reduced fatigue and improved quality of life were observed in MS patients. But the drug did not prevent the progression of the disease. Keywords: cognitive function, vitality, overall life satisfaction, pain, fatigue

Item Type: Article
Additional Information: cited By 0
Subjects: Neuroscience
Nutrition
Divisions: Faculty of Medicine > Basic Sciences > Department of Nutrition
Depositing User: ART . editor
Date Deposited: 04 Mar 2019 11:00
Last Modified: 04 Mar 2019 11:00
URI: http://eprints.kaums.ac.ir/id/eprint/3358

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