The effect of ferric chloride on superficial bleeding

Nouri, S. and Sharif, M.R. and Sahba, S. (2015) The effect of ferric chloride on superficial bleeding. Trauma Monthly, 20 (1). pp. 7-10.

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Background: Controlling superficial bleeding, despite all the progress in surgical science, is still a challenge in some settings. Objectives: This study assesses the hemostatic effects of ferric chloride and compares it with the standard method (suturing technique) to control superficial bleeding. Materials and Methods: In this animal model study, 60 male Wistar rats were used. An incision, 2 cm long and 0.5 cm deep was made on rat skin and the hemostasis time was recorded using ferric chloride at different concentrations (5, 10, 15, 25, and 50) and then using a control (i.e. control of bleeding by suturing). The skin tissue was examined for pathological changes. Finally, the obtained data were entered into SPSS (ver. 16) and analyzed using Kruskal-Wallis test, Mann-Whitney, Kolmogorov-Smirnov, and Wilcoxon signed ranks test. Results: The hemostasis time for the ferric chloride concentration group was significantly less than for the control group (P < 0.001). Conclusions: Ferric chloride may be an effective hemostatic agent to control superficial bleeding in rats. Copyright © 2015, Trauma Monthly.

Item Type: Article
Additional Information: cited By 1
Uncontrolled Keywords: ferric chloride, animal cell; animal experiment; animal model; animal tissue; Article; bleeding; comparative study; concentration response; controlled study; hemostasis; Kolmogorov Smirnov test; Kruskal Wallis test; male; neutrophil; nonhuman; rank sum test; rat; skin; skin edema; skin incision; superficial bleeding; suturing method; treatment outcome; Wilcoxon signed ranks test
Subjects: Medicine
Divisions: Faculty of Medicine > Clinical Sciences > Department of Pediatrics
Depositing User: editor . 2
Date Deposited: 07 Mar 2017 19:34
Last Modified: 07 Mar 2017 19:34

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