Vitamin D supplementation in female nurses: The effects on serum 25-hydroxyvitamin D, and non-specific musculoskeletal pain

Alavi, N.M. and Madani, M. and Taghizadeh, M. and Sharif, M.R. (2015) Vitamin D supplementation in female nurses: The effects on serum 25-hydroxyvitamin D, and non-specific musculoskeletal pain. Journal of Musculoskeletal Research, 18 (2).

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Purpose: To investigate the effect of weekly single high dose Vitamin D supplementation on serum 25-hydroxyVitamin D 25(OH)D, and non-specific musculoskeletal pain in female nurses. Methods: In this prospective study in Kashan/Iran, from April 1, 2014, through September 30, 2014, the 150 nurses with Vitamin D deficiency received the weekly pearls of 50,000 units of Vitamin D3 for 10 weeks. The serum level of 25(OH)D was measured before and after supplement therapy. The subjects were also asked to complete the Extended Nordic Musculoskeletal Questionnaire. All analyses were conducted with SPSS version 16. Results: After 10 weeks of intervention there was 21.3±9.8ng/mL increase in 25(OH)D. The 82 nurses (54.7%) had 25(OH)D in normal range, while the 68 nurses (45.3%) were still Vitamin D deficient. Weight could explain 15.4% increase in 25(OH)D. Before intervention 135 (90%), of nurses reported musculoskeletal pain in at least one region, after intervention this number decreased to 72.7%. There was a statistically significant improvement in musculoskeletal pain in neck, shoulders, upper back, lower back, hips/tights, knees, and ankles/feet after intervention. Conclusions: The weekly single high dose of Vitamin D for 10 weeks could resolve Vitamin D deficiency in about half of the patients. Patients with non-specific musculoskeletal pain might benefit from Vitamin D supplementation. © 2015 World Scientific Publishing Company.

Item Type: Article
Additional Information: cited By 0
Uncontrolled Keywords: 25 hydroxyvitamin D; colecalciferol, adult; Article; body mass; body weight; clinical trial; drug megadose; Extended Nordic Musculoskeletal Questionnaire; female; human; Iran; major clinical study; musculoskeletal disease assessment; musculoskeletal pain; nurse; prospective study; vitamin blood level; vitamin D deficiency; vitamin supplementation
Subjects: Nutrition
Divisions: Faculty of Nursing & Midwifery > Department of Nursing - Medical Surgical
Depositing User: editor . 2
Date Deposited: 08 Mar 2017 14:20
Last Modified: 08 Mar 2017 14:20

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