Family history of diabetes and the risk of gestational diabetes mellitus in Iran: A systematic review and meta-analysis.

Moosazadeh, M. and Asemi, Z. and Bagheri-Lankarani, K. and Tabrizi, R. and Maharlouei, N. and Naghibzadeh-Tahami, A. and Yousefzadeh, G. and Sadeghi, R. and Khatibi, S.R. and Afshari, M. and Khodadost, M. and Akbari, M. (2016) Family history of diabetes and the risk of gestational diabetes mellitus in Iran: A systematic review and meta-analysis. Diabetes & metabolic syndrome. ISSN 1878-0334

Full text not available from this repository. DOI: UNSPECIFIED

Abstract

OBJECTIVE Gestational diabetes is the most prevalent metabolic disorder being firstly diagnosed during pregnancy. The relationship between the family history of diabetes and the gestational diabetes mellitus (GDM) has been investigated in several primary studies with a number of contradictions in the results. Hence, the purpose of the present study is to determine the relationship between the GDM and the family history of diabetes using the meta-analysis method. METHOD All published papers in main national and international databases were systematically searched with some specific keywords to find the related studies between 2000 and 2016. We calculated the odds ratio (OR) with 95% confidence interval (CI) in analysis for each study using a random-effect and Mantel-Haenzel method. We also determined heterogeneity among these 33 articles and their publication bias. RESULTS We entered 33 relevant studies of 2516 articles into the meta-analysis process including 2697 women with family history of diabetes mellitus as well as 29134 women without. Of them, 954 and 4372 subjects developed GDM respectively. Combining the results of the primary studies using the meta-analysis method, the overall odds ratio of family history for developing GDM was estimated as of 3.46 (95% CI: 2.80-4.27). CONCLUSION This meta-analysis study revealed that the family history of diabetes is an important risk factor for the gestational diabetes mellitus.

Item Type: Article
Subjects: Medicine
Nutrition
Multidisciplinary
Divisions: Faculty of Medicine > Basic Sciences > Department of Nutrition
Depositing User: editor . 2
Date Deposited: 08 Jan 2017 16:38
Last Modified: 28 Feb 2017 15:21
URI: http://eprints.kaums.ac.ir/id/eprint/25

Actions (login required)

View Item View Item