Effects of different routes of Corticosteroids administration on Asthma attack

Razi, E. and Jalali, M. and Moosavi, G.A. (2002) Effects of different routes of Corticosteroids administration on Asthma attack. Feyz Journal of Kashan University of Medical Sciences, 6.

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Official URL: http://feyz.kaums.ac.ir/article-1-328-en.html


Background: Asthma is a prevalent chronic pulmonary disease presented in 20 of population. Steroids have been shown to be effective in asthma treatment however, controversies are arisen in the route of administration. The present study was conducted in a private clinic in Kashan to determine the effects of different routes of corticosteroid administration (Oral, injection and inhalation) on asthma attack.Materials and Methods: 120 patients had entered this clinical trial. Patients were distributed in three groups oral, injection and inhalation group. All subjects received salbutamol. Spirometry was performed before and after the therapy and then results were analyzed.Results: The study population included 63 males (52) and 57 females (48) with the mean age of 39.9 years. Comparison of FEF25-75, FEV1 and FVC results showed non-significant differences between the oral and injection groups, however, they were more effective than inhalation corticosteroids.Conclusion: Administration of corticosteroids either orally or by injection can be easily used to control asthma attack. Inhalation therapy is less effective and is not recommended.

Item Type: Article
Subjects: Pharmacology, Toxicology and Pharmaceutics
Divisions: Feyz journal
Depositing User: ART . editor
Date Deposited: 14 May 2017 14:23
Last Modified: 03 Jun 2017 14:00
URI: http://eprints.kaums.ac.ir/id/eprint/2375

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