Association between the multiple sclerosis and relaxation time of MR in brain tissue

Anvari, S.S and Oghabian, M.A and Riahi Alam, N. and Ghanaati, H. (2004) Association between the multiple sclerosis and relaxation time of MR in brain tissue. Feyz Journal of Kashan University of Medical Sciences, 7.

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Official URL: http://feyz.kaums.ac.ir/article-1-205-en.html
DOI: UNSPECIFIED

Abstract

Background: Contrast of conventional MRI images is influenced by different parameters such as T1, T2, and proton density that may lead to invisibility and undetectibility of some small lesions in the normal appearing white matter (NAWM) in patients with multiple sclerosis (MS). Each brain tissue has specific values for T1 and T2 that usually changes in different pathologic lesions, thus, these differences may help clinician to differentiate different pathologies by measurement of these relaxation times. The present study was conducted to determine the association between the multiple sclerosis and relaxation time of MR in brain tissue. Materials and methods : For this case-control study, 15 patients with MS and 15 normal subjects were selected. MRI was performed in Imam hospital on 1.5 Tesla  Picker MRI system. First, T1 and T2 maps were computed from two images using spin echo (SE) and inversion recovery (IR) pulse sequences with optimization of interpulse time intervals TE, and TR to minimize errors. Then, T1 and T2 values of brain tissues were measured. Results : Results have revealed that not only T1 and T2 values in MS plaques increase significantly (P

Item Type: Article
Subjects: Medicine
Divisions: Feyz journal
Depositing User: ART . editor
Date Deposited: 13 May 2017 17:08
Last Modified: 23 May 2017 12:06
URI: http://eprints.kaums.ac.ir/id/eprint/2278

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