Methylen blue usage in diagnosis of extent of traumatic necrotizing liver injury

Behdad, Akbar and Memari, Mohammad Reza and Ghasemi, Ali Akbar and Hosseinpour, Mehrdad (2006) Methylen blue usage in diagnosis of extent of traumatic necrotizing liver injury. Feyz Journal of Kashan University of Medical Sciences, 10.

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Background: In this study, the effect of methylene blue in differentiation of necrotic and vital areas of traumatic liver of rabbit was studied. Materials and Methods: Twenty healthy rabbits were selected and divided in two equal groups randomly. Through a midline incision, rabbit's abdomen was opened. In the case group liver was traumatized for necrosis by hemostat. Then, through portal vein a blue catheter (22 G) was inserted. Sterile water was added to 0.2 cc of 2 methylen blue whose volume reached to 2 ml. Then, it was injected through the catheter. the times related to painting and discoloration were recorded. Wilcixon and linear regression analysis were used to analyze the data. Results: The mean time of liver painting and discoloration were 17.7 ± 1.4 and 53.6 ± 3.2 in controls. In the case groups, there was no painting. There was a linear correlation between painting and discoloration times (r=0.51, P=0.012). Conclusion: Methylen blue can be used to differentiate necrotizing liver injuries.

Item Type: Article
Subjects: Medicine
Divisions: Feyz journal
Depositing User: ART . editor
Date Deposited: 13 May 2017 12:22
Last Modified: 13 May 2017 12:22

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