Taghadosi, M. and Seyedy, M. and Moosavi, G.A. and Fathgharib, J. (2009) A survey on the effect of lovastatin and exercise on serum lipid profiles in hyperlipidemic patients. Feyz Journal of Kashan University of Medical Sciences, 13.
Full text not available from this repository.Abstract
Background: High lipid serum level was a risk factor for cardiovascular disease. This study was performed to evaluate the effects of Lovastatin and exercise on hyperlipidemic patients at Kashan Shahid Beheshti Hospital during 2005–6. Materials and Methods: This randomized clinical trial study was carried out on hyperlipidemic patients (age>30 years). After registering the personal data of the patients the participants were selected based on the inclusion criteria (HDL<35 mg/dl, LDL≥160 mg/dl, TG≥200 mg/dl, Chol≥200 mg/dl). the Lovastatin group (40 mg/daily) and the exercise group (waking 35 minutes/day, 3 times a week). The clinical tests were repeated for six consecutive weeks. Data were analyzed using t-Test, Wilcoxon Signed Rample Test, Kolomogorou-Smirnov Test, Mann-Whitney Test, levens Test. Results: from Ninety-six out of 150 cases were hyperlipidmic signifying that only 80 (59 male, mean age 55.12±8.4 case and control 55.35±9.2 years) out of 150 hyperlipidemic patients were qualified for the study. The mean decrease in TG level between the Lovastatin and exercise groups were 21.4 (P=0.2) and 20.5 mg/dl (P=0.2), respectively. The mean decrease in cholesterol level between Lovastatin and exercise groups were 41.3 and 1.5 mg/dL (P=0.001). The mean decrease in LDL level between Lovastatin and exercise groups were 35.8 and 8.5 mg/dl (P<0.001), respectively. Finally, the mean increase in HDL level between Lovastatin and exercise groups were 5.4 and 0.4 mg/dl. Conclusion: exercise may be effective for decreasing the LDL. While Lovastatin could decrease the total cholesterol TG and increase HDL levels, using a combination is recommended for hyperlipidemic patients.
| Item Type: | Article |
|---|---|
| Subjects: | Pharmacology, Toxicology and Pharmaceutics |
| Divisions: | Feyz journal |
| Depositing User: | ART . editor |
| Date Deposited: | 10 May 2017 14:57 |
| Last Modified: | 28 May 2017 12:01 |
| URI: | http://eprints.kaums.ac.ir/id/eprint/2013 |
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