Morshedi, M. and Gol, A. (2015) The effect of Ginger powder on the elimination of Acetaminophen-induced renal toxicity in adult male rats. Feyz Journal of Kashan University of Medical Sciences, 18.
Full text not available from this repository.Abstract
Background: Acetaminophen has been recognized as an analgesic, but its overuse can cause renal and hepatic toxicity. Ginger as a spice has been used in traditional medicine since the year 2000 in China and Iran. The purpose of the present study was to evaluate the effect of Ginger on renal function in toxicity induced by Acetaminophen. Materials and Methods: This experimental study was performed on 24 male Wistar rats. After 24 hours of fasting, animals were allocated into four groups as follows: the control and Ginger groups each receiving normal saline the Acetaminophen and Acetaminophen+Ginger groups each receiving Acetaminophen (1000 mg/kg) via the gavage. After eight hours, the control and Acetaminophen groups received normal saline and the Ginger and Acetaminophen+Ginger groups received Ginger powder (500 mg/kg). After twelve hours, animals were sacrificed and blood samples were taken to evaluate the serum urea and creatinine. Moreover, the measurement of creatinine in the urine was done.Results: Serum creatinine levels were increased and decreased in the Acetaminophen group (P
| Item Type: | Article |
|---|---|
| Subjects: | Pharmacology, Toxicology and Pharmaceutics |
| Divisions: | Feyz journal |
| Depositing User: | ART . editor |
| Date Deposited: | 07 May 2017 16:25 |
| Last Modified: | 28 May 2017 13:37 |
| URI: | http://eprints.kaums.ac.ir/id/eprint/1586 |
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