Association between serum lactate and postoperative outcomes following coronary artery bypass graft surgery

Hasanshiri, F. and Pourabbasi, M.S. and Moosavi, G.A. and Fatahi, M. and Kianfar, A.A. and Seyedi, H.R. and Mirhoseini, F. and Mahdian, M. (2017) Association between serum lactate and postoperative outcomes following coronary artery bypass graft surgery. Feyz Journal of Kashan University of Medical Sciences, 20.

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Official URL: http://feyz.kaums.ac.ir/article-1-3225-en.html
DOI: UNSPECIFIED

Abstract

Background: Increased serum lactate during cardio-pulmonary bypass is associated with high mortality and cardiac complications up to 10-20 percent. The aim of this study was to evaluate the effect of serum lactate increase on postoperative outcomes after coronary artery bypass graft (CABG) Surgery. Materials and Methods: This descriptive-analytical study was performed on cases (no=116) undergoing CABG at Beheshti hospital in Kashan between 2013-2014. Demographic data, variables related to surgery, serum lactate level and the time of tracheal extubation, length of stay in intensive care unit (ICU) and hospital post-surgery left ventricular ejection fraction were collected. These data was compared in two groups: Normal serum lactate (< 2 m molliter) and Hyperlactatemia (> 2 m molliter) group. Results: The postoperative hyperlactatemia was observed in 62.1 of patients. There were no significant differences between two groups in time of tracheal extubation, length of stay in ICU and hospital. There was a relationship between the mean postoperative serum lactate and blood sugar, bicarbonate, pH, length of cardiopulmonary bypass and the aortic cross clamping time. There was a significant relationship between the serum lactate increment and the left ventricular ejection fraction decrement. Conclusion: Hyperlactatemia is probably associated with such important factors as high blood sugar, longer duration of aortic cross clamp and cardio-pulmonary bypass time. So controlling such factors can reduce the rate of hyperlactatemia and help postoperative recovery.

Item Type: Article
Subjects: Surgery
Divisions: Feyz journal
Depositing User: ART . editor
Date Deposited: 06 May 2017 14:43
Last Modified: 28 May 2017 12:03
URI: http://eprints.kaums.ac.ir/id/eprint/1440

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